French biotechnology company Ciloa has secured €6.5 million in funding to advance exosome therapy for metabolic diseases.
The funding will support clinical development of Ciloa's candidate APN-sEV for type 2 diabetes and obesity, as well as large-scale manufacturing under Good Manufacturing Practices.
Ciloa's unique bioengineering technology has produced stable Adiponectin associated with exosomes (APN-sEV), showing promise in preclinical trials against obesity and diabetes.
The company plans to begin phase I clinical trials in 2027 and phase IIa in 2028 for its innovative drug composed of adiponectin introduced via small extracellular vesicles.