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India’s first dengue vaccine: ICMR says phase-3 clinical trial enrolment to be completed by October

  • India is conducting phase-3 clinical trials for its first dengue vaccine with 8,000 participants receiving either the vaccine or a placebo across various centers.
  • The trial is sponsored by the Indian Council of Medical Research (ICMR) and Panacea Biotec, with the results of the phase-1/2 trial showing no safety concerns for the one-shot vaccine.
  • The phase-3 trial, aiming to evaluate the vaccine's efficacy and safety, began in August last year and involves a multi-centre, double-blind, randomised, placebo-controlled approach.
  • Dengue is a significant public health issue in India, with the global incidence of the disease on the rise. Approximately 75-80% of dengue infections in India are asymptomatic, and the disease poses a higher risk for children and can lead to severe conditions in adults.

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