Material-UI's grid system is implemented using the Grid component, offering flexibility with Flexbox properties.There are container and item types of grid components for fluid layouts across different screen sizes.Import the Grid component in JavaScript using 'import Grid from '@mui/material/Grid';'Containers give the Grid component flex container properties, and items give flex item properties.Material Design's grid system ensures visual balance and adaptability to various screen sizes.MUI Grid uses standard CSS Flexbox with breakpoints for responsive web apps.Installation of MUI in React involves installing necessary dependencies and setting up components.Grid properties like spacing, fluid grids, auto-layout, nested grids, and responsive layouts are explained.MUI's Stack component is suggested for vertical layouts instead of using the Grid system.Best practices include optimizing performance with virtualization techniques and adding borders to Grid items.