<ul data-eligibleForWebStory="true">Affordable access to more effective diabetes treatment is hindered in low- and middle-income countries by high prices resulting from patent barriers.The World Health Organization is considering adding GLP-1 RAs to its Essential Medicines List to encourage procurement and affordability.Generic competition could lower the price of semaglutide from $100–300 to under $6 per month.Pharmaceutical companies extend monopolies through tactics like evergreening, hindering affordability.Novo Nordisk and Lilly hold multiple patents on diabetes drugs, despite the core compound patents expiring soon.The clash between patent monopolies and generic manufacturers, like in the Novo Nordisk vs. Dr Reddy's Laboratories case, impacts drug affordability.A ruling in favor of generic manufacturers could lead to earlier availability of generic semaglutide and price reductions.The outcome of legal battles in India will influence access to diabetes medication in LMICs.The court decisions will determine whether affordable access to diabetes treatment is prioritized over patent enforcement.The results could impact the timely access to crucial diabetes medications for patients in resource-constrained countries.