The async attribute in the <script> tag allows the browser to continue parsing the HTML while fetching and executing the script file.The defer attribute in the <script> tag also allows the browser to continue parsing the HTML while fetching the script file, but defers the execution until the HTML parsing is complete.The async attribute is useful when the script files are independent of each other and don't have a direct relationship with the DOM.The defer attribute is useful when the scripts are dependent on each other or need to interact with the DOM, and the execution order needs to be maintained.