Decentralised science (DeSci) is compared to the early days of decentralised finance (DeFi) in 2019.DeSci aims to revolutionize science and healthcare through blockchain technology.It emphasizes transparency, decentralization, incentives, and global collaboration to make science more accessible and trustworthy.Leading DeSci projects include OriginTrail, VitaDAO, Rifampicin, and HairDAO.