Enabling agility in large organizations involves empowering teams through four decision rights guardrails.Decentralization and context-sharing are advocated by Itamar Gilad to address decision-making challenges.Strategies for optimizing team topologies to enhance flow and productivity are offered by Petra Wille and Elias Lieberich.Organizational culture often undermines the autonomy promised by Agile principles, as highlighted by Willem-Jan Ageling.