Netflix's 'Big Mouth' final season features a star-studded voice cast including Natasha Lyonne, Megan Thee Stallion, and Jordan Peele.The animated series has run for eight seasons and over 200 guest stars, winning five Emmys and inspiring the spin-off 'Human Resources.'Nick Kroll voices multiple characters like Nick, Lola, and hormone monsters. John Mulaney, Jessi Klein, and Maya Rudolph also play key roles.Ayo Edebiri took over voicing Missy from Jenny Slate to explore the character's Black identity.Thandiwe Newton, Jason Mantzoukas, Andrew Rannells, and David Thewlis voice notable characters like Mona, Jay, Matthew, and The Shame Wizard.Jean Smart plays Depression Kitty, and Maria Bamford voices Tito the Anxiety Mosquito.Celebrities like Zazie Beetz, Megan Thee Stallion, and Jordan Peele also make guest appearances in the show.Brian Tyree Henry, Natasha Lyonne, Ali Wong, and Keke Palmer are among the other talented actors lending their voices on 'Big Mouth.'The final season continues to explore the trials and tribulations of adolescence through humor and a talented voice cast.The diverse and star-studded ensemble truly brings the characters of 'Big Mouth' to life in their animated form.