To clean your Mac screen and body, use water in a spray bottle and a clean microfiber cloth for a simple and effective approach.Consider using a Giottos Rocket Blower to remove dust without the need for canned compressed air.Start cleaning by turning off and unplugging your computer, then proceed to wipe it down with a damp cloth to avoid liquid damage.Organize your Mac's hard drive by navigating to Storage in System Settings to manage and delete unused applications and files.Use a tool like AppCleaner to ensure complete removal of files and folders when uninstalling applications.In the Documents section of storage, delete unnecessary files and DMGs to free up space on your Mac.Install Bartender to customize and hide menu bar items, keeping it tidy and organized for easy access.Manage Login Items in System Settings to optimize your system's boot-up process by reducing the number of programs launched.Use tagging in Finder to categorize and locate files efficiently, making it easier to find important documents.Consider using Alfred as a powerful tool for file organization and quick app launching in macOS.