Disabling buttons with jQuery can prevent premature clicks, especially when forms are being filled or loading.In HTML, buttons can be disabled by adding the disabled attribute statically, but jQuery allows dynamic disabling based on user actions.To disable a button using jQuery, you can use $('#myButton').prop('disabled', true); and to enable, $('#myButton').prop('disabled', false);.jQuery can be used to disable buttons on form submission or based on specific inputs, enhancing user experience on web pages.