Pathologic 3 will have a different gameplay compared to its predecessor, with players embodying the Bachelor instead of a roaming surgeon.
The open world in Pathologic 3 will not be freely explorable like before, but will involve isolated pockets, loading screens, map plotting, and fast travel, which has disappointed some fans.
Ice-Pick Lodge developers defended their decision to change the game's traversal stating that they wanted to try new things creatively and commercially, as sequels to indie games often sell worse than the originals.
While the studio is maintaining the fragmented open world, they are addressing issues like the survival meter for the hero's mental state and performance improvements before the game's release later this year.