<ul><li>U.S.-based biotech firm, Colossal Biosciences, has revived the dire wolf, a species extinct for 12,500 years, through genetic engineering, marking the world's first true de-extinction event.</li><li>Using ancient DNA from fossils, Colossal reconstructed the high-quality genomes of dire wolves and edited modern gray wolf DNA to include key genetic variants unique to dire wolves.</li><li>Three dire wolf pups, Romulus, Remus, and Khaleesi, were successfully born through the cloning process, exhibiting signature traits of their ancestors.</li><li>The implications of de-extinction include conservation potential to bolster biodiversity and restore ecosystems, as well as ethical considerations and debate about the ecological impact and funding allocation.</li></ul>

Reviving the Dire Wolf: A Leap in De-Extinction Technology

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