Python is a versatile programming language used by developers for automation, web development, data science, etc.To set up Python on macOS, it is recommended to install up-to-date versions instead of using the pre-installed Python versions.Popular tools for setting up Python on macOS include Homebrew for package management and pyenv for version management.Visual Studio Code is a popular code editor for Python development on macOS, and it can be customized with extensions like Code Runner.