The Interface Segregation Principle (ISP) ensures that no client is forced to depend on methods it does not use.
Large interfaces should be broken down into smaller, more specific interfaces to prevent burdening classes with irrelevant functionality.
Example: A large interface called IAnimal is split into smaller interfaces such as IEater, IFlyer, and ISwimmer to allow classes to implement only the interfaces they need.
Benefits of following ISP include avoiding unnecessary methods, improved maintainability, and better flexibility.