<ul data-eligibleForWebStory="true">Santiment's latest report highlights the top altcoin projects with significant increases in whale transactions over $100,000.Ethereum Name Service (ENS), Compound (COMP), and Virtuals Protocol (VIRTUAL) are leading the list of top gainers.Altcoins like ENS have shown a notable increase in whale transaction volume, indicating potential price volatility.The top gainers in whale activity include ENS, COMP, VIRTUAL, Dai, USD Coin, Mantle, OCD, WETH, and SPX6900.Santiment cautions that such whale activity can signal institutional accumulation, reallocation, or liquidation, impacting price swings.The report suggests that traders should combine whale activity signals with technical and on-chain indicators before making trading decisions.