TypeScript is a highly expressive language that allows writing algorithms using types alone but has limitations like maximum tuple length.Node.js developers handle TypeScript for types and JavaScript for values, requiring strict definition of custom types for full utilization.TypeScript includes string, number, boolean as primitive types, with any being the default when no type is specified.Literal types in TypeScript allow for more specific type expressions, such as 'hello world' or the number 10.TypeScript distinguishes between undefined and null types, helping differentiate between explicitly set and unspecified properties.The never type in TypeScript represents an empty set, with unique behavior when used in conditional types.Union types in TypeScript allow for combining types using the pipe symbol, while intersection types represent common elements using '&'.Generic types in TypeScript enable writing complex types concisely by defining types with parameters, offering flexibility in type definitions.Conditional types in TypeScript allow for branching based on type conditions, with the infer keyword inferring types based on conditions.The as keyword in TypeScript is used for explicit type assertion, especially in scenarios where the compiler needs help identifying types.