Setting up an AWS CodePipeline for deploying artifacts to multiple S3 buckets is useful for scenarios like deploying static websites across different environments or regions.
Prerequisites include an AWS account with necessary permissions, two or more S3 buckets configured for static website hosting, and a source artifact stored in an S3 bucket.
The step-by-step setup involves creating a pipeline, adding a source stage with details of source bucket and object key, and adding deploy stages for each target bucket with actions like extracting files before deployment.
Benefits of this setup include automation that streamlines deployment, consistency in deployment artifacts across target buckets, and scalability to extend to more buckets or regions.