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A Novel Graph Transformer Framework for Gene Regulatory Network Inference

  • A novel Graph Transformer Framework (GT-GRN) for Gene Regulatory Network (GRN) inference is introduced.
  • The GT-GRN model incorporates autoencoder embeddings, prior knowledge from GRN structures, and positional information of genes.
  • Using raw data, the autoencoder captures gene expression patterns to preserve biological signals.
  • Experimental results demonstrate that GT-GRN outperforms existing GRN inference methods in terms of accuracy.

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