<ul><li>Protein Language Models (pLMs) integrated with Large Language Models (LLMs) have advanced computational protein science.</li><li>pLMs have improved protein structure prediction and can predict structures for orphan proteins without relying on multiple sequence alignments.</li><li>pLMs have been utilized in antibody design, enzyme engineering, and drug discovery, offering more controlled and cost-effective alternatives to traditional methods.</li><li>In drug discovery, pLMs help predict drug-target interactions, accelerating the screening of potential drug candidates.</li></ul>

Advancing Protein Science with Large Language Models: From Sequence Understanding to Drug Discovery

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