The linear-quadratic model and the multi-target single-hit (MTSH) model are discussed as alternatives to describe cell survival curves following exposure to ionizing radiation.
Both models have parameters that affect cell survival probability, with differences in behavior at small and large radiation doses.
The MTSH model falls off exponentially at large doses, while the linear-quadratic model falls off quadratically. Each model provides insights into cell survival under radiation.
The choice between these models depends on experimental data and assumptions, with considerations for extrapolating behavior from large dose measurements to determine appropriate model parameters.