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Biomimetic Two-Stage Micro-Nanomotor Featuring Weak Acid-Triggered Nanomotor Release
- Researchers have developed a two-stage micro@nanomotor system inspired by suckerfishes and sharks, utilizing NIR light propulsion and weak acid-triggered nanomotor release for precise cargo delivery.
- The micro@nanomotor design mimics how suckerfishes detach from sharks to forage independently, enabling selective release of nanomotors in response to environmental pH changes.
- The system comprises a micromotor host with Janus gold-platinum nanomotors that detach in weakly acidic conditions, facilitating targeted delivery in complex environments like tumor extracellular spaces.
- Directional motion is achieved through self-thermophoresis under NIR light, while nanomotors engage in self-diffusiophoretic movement driven by hydrogen peroxide for independent navigation.
- This innovative propulsion mechanism combines light actuation with responsive release, addressing challenges in micro/nanomotor adaptability within biological milieus for tasks like drug delivery and environmental detoxification.
- The core-satellite architecture allows for high payload capacity of functional nanomotors on a single micromotor platform, maximizing efficiency in targeted therapeutic applications.
- The research demonstrates adaptability in fluctuating environments by using pH-sensitive Janus nanomotors, offering operational flexibility in biochemically diverse conditions.
- Integration of biologically inspired motion strategies with smart materials enables remote control of micromotors via NIR light and environmentally triggered nanomotor release for enhanced versatility.
- Applications extend beyond medicine to environmental remediation, utilizing autonomous nanomotors for pollutant degradation, water treatment, and in situ environmental monitoring.
- This biomimetic approach showcases the potential of engineered microsystems inspired by natural cooperative behaviors, fostering advancements in intelligent nanomachines for various applications.
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