AWS's 6 pillars of architecture are crucial for cloud builders to ensure secure, efficient, and resilient systems.The pillars include Operational Excellence, Security, Reliability, Performance Efficiency, Cost Optimization, and Sustainability.Key tips include automating processes, enforcing security measures, ensuring reliability through failover strategies, optimizing performance, monitoring costs, and considering sustainability.Following these pillars can help in designing architectures that are not just technically sound but also consider people, processes, and purpose.