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Bioengineer
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Cleveland Clinic Awarded $5 Million Grant to Lead Biorepository Coordination for Cystic Fibrosis Lung Transplant Research Consortium
- Cleveland Clinic has been awarded a $5 million grant by the Cystic Fibrosis Foundation to continue leading the Biorepository Coordinating Center for the Cystic Fibrosis Lung Transplant Consortium until 2030.
- This grant emphasizes the importance of enhancing scientific understanding to improve long-term outcomes for lung transplant recipients, particularly those with cystic fibrosis, through collaborative research.
- The Consortium involves 15 top institutions working together to study and combat complications post lung transplantation.
- Chronic Lung Allograft Dysfunction (CLAD) is a major cause of lung transplant failure, and the research aims to unravel its complexities for better outcomes.
- The Biorepository Coordinating Center gathers biological specimens and clinical data to support research on CLAD, focusing on genomics, proteomics, and other analyses.
- The goal is to identify biomarkers predicting CLAD onset, progression, and therapy response to advance precision medicine in lung transplantation.
- By standardizing protocols and fostering research collaboration, the initiative seeks to improve transplant candidate selection and post-transplant care for better outcomes.
- The Consortium brings together expertise from various institutions to accelerate translational research and develop new therapies against CLAD.
- This work addresses the urgent need for improved understanding and treatments for CLAD, a critical issue affecting lung transplant longevity.
- The grant supports ongoing biospecimen collection, research expansion, and integration of emerging technologies to enhance the impact of the biorepository on global research initiatives.
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