Researchers have developed a data-driven Model Predictive Control (MPC) algorithm for deep brain stimulation (DBS) in the treatment of Parkinson's disease (PD).
Closed-loop DBS (CLDBS) utilizes neural oscillations as a feedback signal, resulting in improved treatment outcomes and reduced side effects compared to open-loop DBS.
The proposed algorithm uses a multi-step predictor based on input-convex neural networks to model the future evolution of beta oscillations, improving prediction accuracy and simplifying online computation.
Through simulations and tests with PD patients, the algorithm achieved significant reductions in tracking error and control activity compared to existing CLDBS algorithms, offering a potential advancement in DBS treatment for PD and other diseases.