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Divergent Treatment Preferences for Comorbid Obesity and Sleep Apnea Observed Between Patients and Providers

  • A recent study presented at SLEEP 2025 annual meeting reveals differing treatment preferences for obesity and obstructive sleep apnea (OSA) between patients and providers.
  • While continuous positive airway pressure (CPAP) has been the standard treatment for OSA, tirzepatide, a GLP-1 and GIP receptor agonist, has gained FDA approval for treating moderate to severe OSA in obese adults.
  • Data from a nationwide survey showed a preference gap between patients and clinicians, with patients leaning towards tirzepatide over CPAP, whereas clinicians expressed a stronger preference for CPAP.
  • There was variation in attitudes towards combination therapy with CPAP and tirzepatide, with healthcare providers more open to it compared to patients.
  • The study highlights the importance of aligning treatment strategies with patient values and expectations to improve adherence and therapeutic success.
  • Obesity complicates the management of OSA, with CPAP addressing mechanical blockages and tirzepatide potentially alleviating apnea severity by reducing weight and improving metabolism.
  • Research emphasizes the need for comparative effectiveness studies to bridge the gap between patient and provider preferences in treating comorbid obesity and OSA.
  • The FDA's approval of tirzepatide signifies a shift in sleep apnea therapeutics, with potential for combined therapy approaches to enhance long-term outcomes.
  • Funding for the study came from the National Institutes of Health and the American Academy of Sleep Medicine Foundation, underscoring its significance and broad impact.
  • In conclusion, understanding patient and provider treatment preferences is crucial for developing personalized care strategies and shaping the future of sleep apnea treatment.

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