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Endoscopic Purse-String Suture Heals Intestinal Fistulas

  • In gastrointestinal surgery, postoperative intestinal anastomotic fistulas (PIAF) pose challenges due to high morbidity; a study highlights endoscopic purse-string suturing (EPS) as a minimally invasive solution.
  • Over a study period from 2015 to 2024, EPS showed technical success in 87.3% of cases for sealing fistulas, with a clinical success rate of 63.6%.
  • No significant outcome differences were found between internally and externally referred patients, indicating EPS's reproducibility across diverse settings.
  • Patients with prior ostomy creation had a higher clinical success rate post-EPS, suggesting ostomies may aid in fistula closure.
  • Early EPS intervention within two months of diagnosis yielded better outcomes, emphasizing the importance of timely treatment.
  • Pre-existing anastomotic strictures negatively impacted clinical success rates, necessitating tailored strategies for these cases.
  • EPS demonstrated a safe profile with minimal complications, underlining its effectiveness and durability in fistula management.
  • Technical details of EPS involve suturing the fistula's orifice endoscopically, promoting tissue healing and eventual closure through granulation tissue formation.
  • The study advocates for selective stoma creation pre-EPS and emphasizes 'time-sensitive intervention' for optimal outcomes in complex fistula cases.
  • EPS showcases the potential of endoscopic innovations in gastrointestinal surgery, offering a minimally invasive approach for challenging complications.

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