Agent-based modeling (ABM) is computationally intensive and not analytically tractable for understanding self-organizing biological systems.
Equation learning (EQL) methods can derive continuum models from ABM data, but concerns about generalizability arise due to the need for extensive simulations for each parameter set.
Multi-experiment equation learning (ME-EQL) introduces two methods - one-at-a-time ME-EQL (OAT ME-EQL) and embedded structure ME-EQL (ES ME-EQL) to enhance generalizability across parameter space.
Demonstrated using birth-death mean-field and on-lattice agent-based models, ME-EQL methods reduce relative error in recovering parameters from agent-based simulations, with OAT ME-EQL showing better generalizability.