<ul data-eligibleForWebStory="true">Whole Slide Imaging (WSI) is crucial in modern cancer diagnostics for examining tissue specimens in detail.WSIs are prone to artifacts during slide preparation and scanning, potentially impacting downstream image analysis.A study proposes and evaluates three robust artifact detection approaches targeting common artifact types in WSIs.The foundation model-based approach (FMA) showed the highest performance in detecting artifacts, accompanied by a quality report scorecard.