Metastatic cancer treatment has evolved with immunotherapy and targeted therapies, offering extended survival prospects but also introducing prognostic uncertainty.
Metastatic uveal melanoma (mUM), a rare and aggressive eye cancer, faces uncertain outcomes despite therapeutic advancements.
A qualitative study explored how individuals with mUM cope with treatment uncertainties, focusing on hope and realistic expectations.
Participants used meta-cognitive strategies to balance hope and fear, highlighting the emotional challenges of living with mUM.
Uncertainty in Illness Theory helped interpret patient experiences, revealing psychological and social impacts of uncertainty in mUM.
The study emphasized the importance of tailored supportive care for managing uncertainty, anxiety, and communication challenges in mUM patients.
Patients described 'scanxiety' related to routine disease surveillance scans, showcasing the emotional burden of living with metastatic cancer.
Coping with uncertainty in cutting-edge treatments involves 'hoping for the best while preparing for the worst,' requiring nuanced clinical support.
Supportive care strategies should evolve to address the psychological sequelae of prognostic ambiguity in metastatic melanoma treatment.
This study highlights the need for integrated psychological interventions to complement medical advancements in rare cancers like mUM.