Life on Earth is a unique phenomenon, with ours being the only planet known to support life in the form of single-celled organisms.Scientists are exploring the possibility of finding the Last Universal Common Ancestor (LUCA) outside Earth.Mars, once potentially habitable, is currently a barren landscape eyed for signs of past life.Moons like Europa and Enceladus offer hope with their subsurface oceans that could harbor life in the form of single-celled organisms.Extremophiles on Earth have shown that life can exist under extreme conditions previously thought impossible.Bacteria like Helicobacter pylori, found in the human stomach, can survive in highly acidic environments and contribute to gastric diseases.H. pylori's survival mechanisms, such as flagella and urease enzyme, enable it to thrive amidst stomach acidity and cause ulcers.The study of extremophiles gives hope that life could exist in challenging environments on other planets or exoplanets.Life's resilience and adaptation, as seen with H. pylori in the human stomach, offer insights into the potential forms of life beyond Earth.The search for life beyond Earth considers not just habitable conditions but also the possibility of extremophile-like organisms.