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KAIST Pioneers Innovative Retinal Therapy to Restore Vision Loss
- Researchers at KAIST have developed a groundbreaking drug for retinal nerve regeneration to restore vision loss.
- The new therapy targets the PROX1 protein to induce retinal regeneration and achieve significant vision recovery in disease-model mice.
- Importantly, the induced neural regeneration in mammalian retinas offers hope for patients with currently limited treatment options.
- Inspired by aquatic wildlife, the researchers identified PROX1 as a key obstacle in facilitating Müller glia cell dedifferentiation for retinal repair.
- A proposed antibody treatment disrupts PROX1's inhibitory function, promoting Müller glia migration and visual function restoration.
- This innovative therapy shows promise for degenerative retinal diseases and may undergo clinical trials by 2028.
- The collaborative efforts of KAIST researchers and Celliaz Inc. aim to provide effective solutions for retinal disorders.
- The research, published in Nature Communications, emphasizes hope for individuals affected by vision loss.
- The study underscores the commitment to advancing medical science and offering viable treatment avenues for retinal diseases.
- This breakthrough signifies a significant step towards addressing global vision loss challenges and restoring sight to millions.
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