<ul><li>NASA has published guidance on designing safety-critical avionics systems for crewed spaceflight.</li><li>The guidance addresses the need for additional rigor and scrutiny in avionics design for crewed spacecraft.</li><li>One key aspect is specifying the failure hypothesis, which includes categorizing failure modes and mitigating catastrophic effects.</li><li>The failure hypothesis must also include assumptions about relative arrival times of failures and the ability for ground operators to intervene.</li></ul>

Key Considerations When Developing Avionics for Safety-Critical Systems

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