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Image Credit: Bioengineer

Lower dose of mpox vaccine is safe and generates six-week antibody response equivalent to standard regimen

  • A dose-sparing intradermal mpox vaccination regimen was safe and generated an antibody response equivalent to that induced by the standard regimen at six weeks.
  • The study enrolled 225 adults aged 18 to 50 years who had not previously been vaccinated against mpox or smallpox.
  • Participants receiving one-fifth of the standard dose had antibody levels equivalent to those receiving the standard regimen after two weeks.
  • Participants receiving one-tenth of the standard dose had lower antibody levels compared to the standard regimen at all measurements.

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