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Mamba Outperforms HyenaDNA in DNA Sequence Modeling

  • Recent exploration into using the foundation model paradigm for genomics has been done.
  • Mamba is investigated as a backbone for pretraining and fine-tuning in DNA modeling.
  • Mamba scales better than HyenaDNA and Transformer++ in terms of model size.
  • Mamba performs well in utilizing longer context in DNA sequences.

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