A recent study presented at the ATS 2025 International Conference in San Francisco uncovered a surprising link between pharmacologically induced REM sleep suppression and increased survival rates in ALS patients.
REM sleep, crucial for cognitive and emotional functions, can pose risks for ALS patients due to muscle paralysis, leading to respiratory vulnerabilities during sleep.
Research by Dr. Cosmo Fowler from Emory University suggests that REM-suppressing antidepressants may decrease diaphragmatic paralysis, reducing respiratory complications and enhancing patient longevity.
These findings may revolutionize ALS treatment approaches towards targeting sleep architecture to improve survival rates, prompting the need for further prospective clinical trials.