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Image Credit: Physicsworld
Miniaturized pixel detector characterizes radiation quality in clinical proton fields
- Proton therapy is a precise cancer treatment depositing energy at a specific depth to spare healthy tissue.
- There is a growing interest in considering proton linear energy transfer (LET) for treatment optimization.
- Researchers at the Institute of Nuclear Physics used miniaturized semiconductor pixel detector Timepix3 for LET characterization of proton therapy.
- Experiments were conducted at the Cyclotron Centre Bronowice using Timepix3 for intensity-modulated proton therapy (IMPT).
- The Timepix3 detector provided detailed LET spectra measurements for treatment plans in homogeneous and heterogeneous phantoms.
- Experiments demonstrated agreement between measured and simulated LET values in phantom irradiation.
- Single field IMPT plan measurements in a head phantom showed close agreement of deposited energy and LET spectra.
- Clinical translation of LET measurement using Timepix3 requires upgrading beam delivery systems for low beam current monitoring.
- Implementing LET measurements with Timepix3 could enhance treatment planning and effectiveness in proton therapy.
- The compact and commercially available Timepix3 detector holds promise for widespread application in proton therapy centers.
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