A naukri.com initiative
Bioengineer
14h
280
Image Credit: Bioengineer
Nano-Hydroxyapatite Boosts Chewing, Reduces Inflammation
- A study published in BioMedical Engineering OnLine revealed the benefits of nano-hydroxyapatite (nano-HA) fillers in dental restoration, improving masticatory function and reducing inflammation in patients with periapical inflammation.
- Periapical inflammation, caused by bacterial infection in the root canal, was addressed by incorporating nano-HA fillers that promote tissue regeneration and control inflammation more effectively than traditional materials.
- The research compared the outcomes of standard root canal therapy and nano-HA filling in 98 patients, showing significant improvements in bite force, chewing efficiency, and decreased levels of inflammatory cytokines with nano-HA.
- Nano-HA demonstrated superior masticatory performance enhancement and an anti-inflammatory effect by reducing pro-inflammatory cytokines like IL-1β and TNF-α in gingival sulcular fluid.
- Patients treated with nano-HA showed better sealing of root canals and accelerated healing rates, potentially due to the nano-scale dimensions that enhance bonding with dentin and reduce microleakage.
- The sustained reduction in inflammation post-treatment suggests long-term benefits for periodontal health, highlighting nano-HA's biocompatibility and osteoconductivity in dental restorations.
- Nano-HA's dual function of structural support and biological homeostasis elevates it beyond conventional filling materials, with implications for improved proprioception and oral health indicators.
- Further exploration into nano-HA's anti-inflammatory mechanisms and long-term clinical trials are warranted to validate its efficacy and potential for personalized nanomaterial therapies in dentistry.
- The study underscores the intersection of materials science and biomedical engineering, advocating for the integration of nano-scale biomaterials to revolutionize endodontic treatments and enhance patient outcomes.
- Xie and colleagues' work emphasizes nano-hydroxyapatite as a promising solution for periapical inflammation, prioritizing biological functionality alongside mechanical performance for future material innovations in dentistry.
- The findings pave the way for advancements in regenerative strategies beyond dentistry, showcasing the transformative potential of nano-HA and technology-driven approaches to patient care.
Read Full Article
16 Likes
For uninterrupted reading, download the app