A naukri.com initiative
Bioengineer
7h
333
Image Credit: Bioengineer
Nicotinamide Boosts Gut Microbes, Speeds COVID-19 Recovery
- A study revealed the role of nicotinamide in boosting gut microbial metabolism and accelerating COVID-19 recovery in patients with mild-to-moderate cases.
- Nicotinamide, a form of vitamin B3, reshapes the gut microbial landscape, enhancing microbial pathways that aid in recovery from SARS-CoV-2 infection.
- By influencing key microbial enzymatic functions, nicotinamide optimizes NAD+ biosynthesis and tryptophan metabolism, improving cellular energy and immune cell function.
- The study showed that nicotinamide supplementation led to faster resolution of symptoms like fatigue, cough, and malaise in COVID-19 patients.
- Nicotinamide promoted the proliferation of beneficial bacteria like Lactobacillus and Bifidobacterium while reducing opportunistic pathogens, rebalancing the gut ecosystem.
- Participants supplemented with nicotinamide alongside standard care showed statistically significant accelerated recovery, indicating the potential of this dietary intervention.
- The study proposed a gut-lung axis where nicotinamide reinforced gut barrier integrity, possibly mitigating pulmonary inflammation in COVID-19 patients.
- Nicotinamide was well-tolerated with minimal adverse effects, suggesting its safety and potential as an adjunct therapy for COVID-19 and other respiratory viral infections.
- Future research aims to explore nicotinamide's efficacy in diverse populations and its interactions with antiviral and immunomodulatory therapies for enhanced treatment outcomes.
- This study underscores the importance of gut microbiome modulation in immune responses to viral infections, opening new avenues for precision nutrition in infectious disease management.
Read Full Article
20 Likes
For uninterrupted reading, download the app