Struct layout in Go refers to how fields within a struct are arranged in memory, including padding for alignment.Proper struct layout is crucial for memory efficiency, cache utilization, and performance optimization in applications.Understanding padding and alignment rules is key to optimizing struct layouts.Ordering fields by size and grouping related fields are recommended best practices for struct layout.Optimizing struct layout can lead to reduced memory usage, better cache performance, and improved serialization.A practical benchmark comparing poor and optimized struct layouts showed significant improvements in memory usage and performance.The optimized layout reduced memory usage by 50% and showed faster allocation and field access speed.Practical scenarios where struct layout optimization matters include web servers, data processing, game development, and IoT devices.Tools like viztruct can help visualize and optimize struct layouts automatically.Optimizing struct layout is essential for writing efficient Go code, especially in resource-constrained environments.