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Oregon State Secures $11.9 Million from Defense Department to Advance Armed Forces Health Initiatives

  • Oregon State University has secured $ 11.9 million in funding from the US Department of Defense to create drug delivery systems to protect soldiers from health threats. The funds come from the Defense Advanced Research Projects Agency’s (DARPA) Hermes program, which aims to deliver therapeutic agents with high precision and minimal side effects.
  • Gaurav Sahay, a nanomedicine researcher at OSU, is leading the project to develop adaptive lipid nanoparticles engineered for aerosolization and intramuscular delivery. These nanoparticles can encapsulate and transport genetic material directly into cells, making them effective delivery vehicles for therapeutics.
  • As per Sahay, the lipid nanoparticles could revolutionize disease prevention, including the potential to fend off infectious diseases, ionizing radiation threats, as well as chemical or biological agents.
  • Oregon State’s team includes subject matter experts from the university, the Oregon National Primate Research Center, and Rare Air Health, Inc.
  • The project is called TALARIA (tailored, adaptive lipid nanoparticles for aerosolization and intramuscular administration) and runs for three years.
  • The funding will allow the team to develop a new drug delivery platform that will allow for safer and more effective delivery of vaccines and therapeutics with minimal side effects.
  • The revolutionary drug delivery system could have implications beyond the military, delivering vital health solutions to the general public.
  • The project will also delve into strategies to manage immune system interactions for maximum nanoparticles therapeutic potential.
  • Overall, this substantial DARPA grant marks a significant step forward towards achieving a vision of more efficient, targeted therapy delivery systems that are safe for both military and civilian use.
  • The lipid nanoparticle drug delivery technology could revolutionize therapeutic applications and change the landscape of drug delivery.

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