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Psilocybin Enters Gastroenterology: Pioneering Psychedelic Trial Targets Treatment-Resistant IBS

  • Dr. Erin E. Mauney pioneers a clinical trial using psilocybin to treat treatment-resistant IBS, bridging mental health, neurobiology, and gastroenterology.
  • The study aims to understand how psilocybin affects interoception and gut-brain communication pathways in IBS patients.
  • Dr. Mauney's research suggests that trauma-induced somatic encoding may contribute to IBS and explores psilocybin's ability to disrupt maladaptive neural patterns.
  • Her work integrates patient-reported outcomes, qualitative narratives, and fMRI data to evaluate and model functional somatic syndromes.
  • By unlocking somatically encoded trauma, Dr. Mauney's research envisions sustained functional recovery for IBS patients.
  • Her study challenges clinical norms by proposing psychedelic therapy for psychological and physiological recalibration, not just symptom suppression.
  • Dr. Mauney emphasizes building authentic relationships with patients and promoting patient-centered care in her research approach.
  • She looks towards wider accessibility of psychedelic treatments and envisions their integration into standard clinical practice for IBS and beyond.
  • The study prompts considerations for applying trauma-informed psychedelic interventions in other treatment-resistant medical conditions.
  • Dr. Mauney's work signifies a transformative shift in gastroenterology and highlights the interconnectedness of mind and body in treating complex illnesses holistically.

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