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Reliability of AI-driven predictions in guiding long COVID drug development

  • AI-driven predictions in Long COVID drug development utilize data integration capabilities to map symptom trajectories and identify potential drugs for trials.
  • AI has accelerated timelines in vaccine development and drug discovery, reducing traditional processes from years to months through epitope prediction and virtual screening.
  • Limitations and risks include data quality issues, algorithmic bias, regulatory gaps, and overstated efficacy claims, highlighting the need for high-quality datasets and validation.
  • AI applications have shown promising impacts in virtual drug screening, predictive phenotyping, and clinical trials optimization, but reliability concerns exist due to limited wet-lab validation and small training cohorts.
  • Collaborative efforts and adherence to FAIR data principles are crucial to enhancing the reliability of AI-driven predictions in Long COVID drug development.

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