A study from Columbia University’s Mailman School of Public Health links climate change to increased arsenic levels in paddy rice, a staple in Asia.Rising global temperatures and higher CO2 levels are projected to elevate inorganic arsenic accumulation in rice by mid-21st century.Climate-induced soil changes facilitate arsenic uptake in rice plants, posing health risks due to toxic inorganic arsenic.Chronic inorganic arsenic exposure from rice is associated with various cancers, cardiovascular diseases, and metabolic disorders.Research spans over a decade and includes diverse rice cultivars to study arsenic uptake under simulated future climate conditions.Models predict a surge in arsenic-related cancers in Asian countries by 2050, highlighting a significant public health challenge.Recommendations include breeding rice with lower arsenic uptake, improved soil management, and public health initiatives to mitigate risks.The study underscores the need for interdisciplinary collaboration and proactive measures to address arsenic exposure in rice crops.Understanding and mitigating arsenic in staple crops is crucial for global health resilience amid climate change impacts.Proactive interventions are essential to prevent escalating health burdens from inorganic arsenic exposure in rice and safeguard human wellbeing.The research highlights the intricate relationship between climate change, food safety, and public health outcomes, urging a science-driven response.