<ul><li>Exposure to altered gravity can cause ocular and brain structural changes to develop during spaceflight; these changes could lead to vision alterations, cognitive effects, or other deleterious health effects.</li><li>Spaceflight Associated Neuro-ocular Syndrome (SANS) is a syndrome unique to humans that fly in space and is not present in terrestrial diseases.</li><li>Over half of crewmembers experience one or more symptoms of SANS, indicating brain structural changes.</li><li>Determining intracranial pressure during spaceflight could improve understanding of SANS mechanisms and the ability to target countermeasures for future missions.</li></ul>

Risk of Spaceflight Associated Neuro-ocular Syndrome

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