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Scientists Create ‘Malteser-Inspired’ Molecules for Potential Targeted Drug Delivery Innovations
- Scientists from Trinity College Dublin have successfully created 'Malteser-like' molecules that could innovate drug delivery and sensing applications.
- By understanding and controlling the self-assembly process of these amino-acid-based ligands, researchers unlocked versatile and different self-assembly structures that could range from gels to structures like Maltesers.
- The researchers found the nature of self-assembly and properties could be significantly influenced through judiciously selecting the amino acids used.
- The newfound ability to exercise control over molecular self-assembly could have immense implications in drug delivery, optical systems and nanoscale engineering.
- For example, researchers can use selective release of therapeutics where they are most needed without causing common side effects attributed to conventional treatment regimens.
- In photonics and optical systems, specific sensors could be developed that could outperform existing technology.
- The investigation was led by Prof Thorfinnur Gunnlaugsson from Trinity Biomedical Sciences Institute, in collaboration with Prof John Boland of CRANN, both from Trinity College Dublin’s School of Chemistry, supplemented by Prof Robert Pal of Durham University.
- The integration of chemistry, biochemistry, material science and physics could enhance the depth and applicability of this research.
- This evolution in material science not only has profound implications for drug delivery systems but could also influence the future of nanotechnology, ushering in a new era for materials engineering.
- The collective insights garnered from this research endeavor will undoubtedly propel future investigations in molecular chemistry and materials science.
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