<ul><li>Scientists at Cincinnati Children’s, Mayo Clinic, and UC San Diego have created the world’s first mini-brain organoids with a functional blood-brain barrier, called "BBB assembloids."</li><li>These assembloids combine brain and blood vessel organoids to model the human BBB's key features. The breakthrough allows for advanced study of neurovascular interactions and holds potential for treating brain disorders like stroke, Alzheimer's, and brain cancer.</li><li>This innovative platform, using patient-derived stem cells, provides a new avenue for drug discovery and therapeutic interventions by mimicking the pathology of cerebral vascular disorders such as cerebral cavernous malformation.</li></ul>

Scientists create world’s 1st mini-brain with working blood-brain barrier

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