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SNMMI LBCA Fellowship for Invasive Lobular Carcinoma Research Awarded to Dr. Randy Ye by Mars Shot Fund

  • Dr. Randy Yeh has been awarded a $100,000 research fellowship by the SNMMI Mars Shot Research Fund and the Lobular Breast Cancer Alliance for pioneering work in imaging invasive lobular carcinoma (ILC).
  • ILC is a challenging subtype of breast cancer, comprising 15% of diagnoses in the US with unique characteristics that evade easy detection through conventional methods.
  • Current imaging techniques like CT scans and standard FDG PET scans often struggle to visualize ILC's dispersed, single-file growth pattern effectively.
  • Dr. Yeh's research focuses on utilizing FAPI PET imaging, which targets fibroblast activation protein specific to cancer-associated fibroblasts in ILC.
  • The study aims to compare FAPI PET with FDG PET in detecting metastatic ILC lesions to improve visualization and potentially impact treatment decisions.
  • Beyond diagnosis, FAPI PET holds promise for targeted radiopharmaceutical therapy by selectively irradiating tumor-supporting fibroblasts.
  • The collaboration between SNMMI, LBCA, and Mars Shot Fund showcases a patient-centered research approach to address the critical need for ILC-specific imaging tools.
  • Dr. Yeh's expertise in cancer biology and molecular imaging positions him well to bridge translational research for improved patient outcomes.
  • The research funded by SNMMI Mars Shot Research Fund seeks to revolutionize breast cancer care by advancing personalized diagnostic and therapeutic strategies.
  • If successful, FAPI PET imaging could set a new standard in ILC imaging, potentially influencing screening protocols and treatment customization globally.

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