Dr. Randy Yeh has been awarded a $100,000 research fellowship by the SNMMI Mars Shot Research Fund and the Lobular Breast Cancer Alliance for pioneering work in imaging invasive lobular carcinoma (ILC).
ILC is a challenging subtype of breast cancer, comprising 15% of diagnoses in the US with unique characteristics that evade easy detection through conventional methods.
Current imaging techniques like CT scans and standard FDG PET scans often struggle to visualize ILC's dispersed, single-file growth pattern effectively.
Dr. Yeh's research focuses on utilizing FAPI PET imaging, which targets fibroblast activation protein specific to cancer-associated fibroblasts in ILC.
The study aims to compare FAPI PET with FDG PET in detecting metastatic ILC lesions to improve visualization and potentially impact treatment decisions.
Beyond diagnosis, FAPI PET holds promise for targeted radiopharmaceutical therapy by selectively irradiating tumor-supporting fibroblasts.
The collaboration between SNMMI, LBCA, and Mars Shot Fund showcases a patient-centered research approach to address the critical need for ILC-specific imaging tools.
Dr. Yeh's expertise in cancer biology and molecular imaging positions him well to bridge translational research for improved patient outcomes.
The research funded by SNMMI Mars Shot Research Fund seeks to revolutionize breast cancer care by advancing personalized diagnostic and therapeutic strategies.
If successful, FAPI PET imaging could set a new standard in ILC imaging, potentially influencing screening protocols and treatment customization globally.