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Image Credit: Bioengineer

Stage of B-Cell Development Influences Effectiveness of Leukemia Treatments

  • Study shows B-cell developmental stage impacts pediatric B-ALL treatment outcomes.
  • Research explores cellular origins of leukemia, aiding risk stratification and therapy targeting.
  • Insights reveal diverse leukemia developmental paths challenging existing concepts on treatment resistance.
  • Identification of multipotent leukemic cells suggests potential treatment evasion mechanism.
  • Novel multipotency score predicts patient response, paving the way for personalized therapies.

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