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The Power of the Pareto Front: Balancing Uncertain Rewards for Adaptive Experimentation in scanning probe microscopy

  • Automated experimentation has the potential to revolutionize scientific discovery, but its effectiveness depends on well-defined optimization targets.
  • Multi-Objective Bayesian Optimization (MOBO) is applied to balance multiple, competing rewards in autonomous experimentation.
  • Using scanning probe microscopy (SPM) imaging, MOBO optimizes imaging parameters to enhance measurement quality, reproducibility, and efficiency.
  • MOBO offers a natural framework for human-in-the-loop decision-making, enabling researchers to fine-tune experimental trade-offs based on domain expertise.

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