A study from the University of Missouri School of Medicine reveals insights on high-dose opioid prescriptions in urban areas.The research highlights the demographic groups most vulnerable to receiving high-dose opioid treatments.Understanding these patterns is crucial for addressing the opioid use disorder (OUD) crisis.The study leveraged data analytics to show how sociodemographic factors impact opioid prescribing trends.Opioids are effective for pain relief but pose risks of dependence and addiction, leading to escalating doses.Factors influencing OUD risk include pain severity, duration of opioid use, dosage, and comorbid conditions.Machine learning techniques were used to analyze over three million Medicaid claim records.Middle-aged adult males under 60 are more prone to high-dose opioid prescriptions.Prescribing behaviors show restraint among younger adults, potentially due to increased awareness.The study found a decline in high-dose opioid prescriptions among individuals over 60, aligning with clinical guidelines.